Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	CST3	HGNC:2475 (HGNC) 1471 (Entrez Gene) 604312 (OMIM) CST3 (Alliance of Genome Resources)	Chr20 p11.21	Chr20:23626706-23638473 (-) GRCh38	age related macular degeneration 11 CST3-related cerebral amyloid angiopathy	P01034 (UniProt | EBI) NM_001288614 (RefSeq)
mouse	Cst3	MGI:102519 (MGI) 13010 (Entrez Gene) Gene Tree Cst3 (Alliance of Genome Resources)	Chr2 73.6 cM	Chr2:148713642-148717432 (-) GRCm39		13010 (NCBI Gene Model) P21460 (UniProt | EBI) NM_009976 (RefSeq)
rat	Cst3	RGD:2432 (Rat Genome Database) 25307 (Entrez Gene) Cst3 (Alliance of Genome Resources)	Chr3 q41			P14841 (UniProt | EBI) NM_012837 (RefSeq)
zebrafish	cst3	ZDB-GENE-030131-373 (Zebrafish Model Organism Database) 791878 (Entrez Gene) cst3 (Alliance of Genome Resources)	Chr13			NP_001026843 (RefSeq) NM_001031673 (RefSeq)
	zgc:163030	ZDB-GENE-060810-77 (Zebrafish Model Organism Database) 566959 (Entrez Gene) zgc:163030 (Alliance of Genome Resources)	Chr13			NP_001082882 (RefSeq) NM_001089413 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.