Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	SRC	HGNC:11283 (HGNC) 6714 (Entrez Gene) 190090 (OMIM) SRC (Alliance of Genome Resources)	Chr20 q11.23	Chr20:37344685-37406050 (+) GRCh38	colon adenocarcinoma colon cancer colorectal cancer ductal carcinoma in situ prostate cancer thrombocytopenia type 2 diabetes mellitus	P12931 (UniProt | EBI) NM_005417 (RefSeq)
mouse	Src	MGI:98397 (MGI) 20779 (Entrez Gene) Gene Tree Src (Alliance of Genome Resources)	Chr2 78.35 cM	Chr2:157265828-157313758 (+) GRCm39	Williams-Beuren syndrome	20779 (NCBI Gene Model) P05480 (UniProt | EBI) NM_001421000 (RefSeq)
rat	Src	RGD:620795 (Rat Genome Database) 83805 (Entrez Gene) Src (Alliance of Genome Resources)	Chr3 q42			Q9WUD9 (UniProt | EBI) NM_001431492 (RefSeq)
zebrafish	src	ZDB-GENE-030131-3809 (Zebrafish Model Organism Database) 325084 (Entrez Gene) src (Alliance of Genome Resources)	Chr23			Q1JPZ3 (UniProt | EBI) NM_001003837 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.