Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	EIF3E	HGNC:3277 (HGNC) 3646 (Entrez Gene) 602210 (OMIM) EIF3E (Alliance of Genome Resources)	Chr8 q23.1	Chr8:108162787-108443496 (-) GRCh38		P60228 (UniProt | EBI) NM_001568 (RefSeq)
mouse	Eif3e	MGI:99257 (MGI) 16341 (Entrez Gene) Gene Tree Eif3e (Alliance of Genome Resources)	Chr15 16.73 cM	Chr15:43113454-43146115 (-) GRCm39		ENSMUSG00000022336 (Ensembl Gene Model) ENSMUSP00000022960 (Ensembl) ENSMUST00000022960 (Ensembl)
rat	Eif3e	RGD:1311521 (Rat Genome Database) 299872 (Entrez Gene) Eif3e (Alliance of Genome Resources)	Chr7			Q641X8 (UniProt | EBI) NM_001011990 (RefSeq)
zebrafish	eif3ea	ZDB-GENE-030131-3827 (Zebrafish Model Organism Database) 325102 (Entrez Gene) eif3ea (Alliance of Genome Resources)	Chr16			Q6DRI1 (UniProt | EBI) NM_200839 (RefSeq)
	eif3eb	ZDB-GENE-050208-283 (Zebrafish Model Organism Database) 561049 (Entrez Gene) eif3eb (Alliance of Genome Resources)	Chr19			Q1LUA8 (UniProt | EBI) NM_001362621 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.