Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	MT1A	HGNC:7393 (HGNC) 4489 (Entrez Gene) 156350 (OMIM) MT1A (Alliance of Genome Resources)	Chr16 q13	Chr16:56638666-56640087 (+) GRCh38		P04731 (UniProt | EBI) NM_005946 (RefSeq)
	MT1B	HGNC:7394 (HGNC) 4490 (Entrez Gene) 156349 (OMIM) MT1B (Alliance of Genome Resources)	Chr16 q13	Chr16:56651886-56653204 (+) GRCh38		P07438 (UniProt | EBI) NM_005947 (RefSeq)
	MT1E	HGNC:7397 (HGNC) 4493 (Entrez Gene) 156351 (OMIM) MT1E (Alliance of Genome Resources)	Chr16 q13	Chr16:56625475-56627112 (+) GRCh38		P04732 (UniProt | EBI) NM_001363555 (RefSeq)
	MT1F	HGNC:7398 (HGNC) 4494 (Entrez Gene) 156352 (OMIM) MT1F (Alliance of Genome Resources)	Chr16 q13	Chr16:56657731-56660698 (+) GRCh38		P04733 (UniProt | EBI) NM_005949 (RefSeq)
	MT1G	HGNC:7399 (HGNC) 4495 (Entrez Gene) 156353 (OMIM) MT1G (Alliance of Genome Resources)	Chr16 q13	Chr16:56666730-56668065 (-) GRCh38		P13640 (UniProt | EBI) NM_001301267 (RefSeq)
	MT1H	HGNC:7400 (HGNC) 4496 (Entrez Gene) 156354 (OMIM) MT1H (Alliance of Genome Resources)	Chr16 q13	Chr16:56669814-56671129 (+) GRCh38		P80294 (UniProt | EBI) NM_005951 (RefSeq)
	MT1L	HGNC:7404 (HGNC) 4500 (Entrez Gene) MT1L (Alliance of Genome Resources)	Chr16 q13	Chr16:56617461-56618818 (+) GRCh38
	MT1X	HGNC:7405 (HGNC) 4501 (Entrez Gene) 156359 (OMIM) MT1X (Alliance of Genome Resources)	Chr16 q13	Chr16:56682470-56684196 (+) GRCh38		P80297 (UniProt | EBI) NM_005952 (RefSeq)
	MT2A	HGNC:7406 (HGNC) 4502 (Entrez Gene) 156360 (OMIM) MT2A (Alliance of Genome Resources)	Chr16 q13	Chr16:56608584-56609497 (+) GRCh38	carotid stenosis type 2 diabetes mellitus	P02795 (UniProt | EBI) NM_005953 (RefSeq)
mouse	Mt2	MGI:97172 (MGI) 17750 (Entrez Gene) Gene Tree Mt2 (Alliance of Genome Resources)	Chr8 46.32 cM	Chr8:94899292-94900196 (+) GRCm39		ENSMUSG00000031762 (Ensembl Gene Model) ENSMUSP00000148308 (Ensembl) ENSMUST00000212806 (Ensembl)
rat	Mt2-ps1	RGD:2324335 (Rat Genome Database) 100362623 (Entrez Gene) Mt2-ps1 (Alliance of Genome Resources)	Chr20
	Mt2A	RGD:1592345 (Rat Genome Database) 689415 (Entrez Gene) Mt2A (Alliance of Genome Resources)	Chr19 p12			P04355 (UniProt | EBI) NM_001137564 (RefSeq)
zebrafish	mt2	ZDB-GENE-030131-4174 (Zebrafish Model Organism Database) 100174951 (Entrez Gene) mt2 (Alliance of Genome Resources)	Chr18			Q7ZSY6 (UniProt | EBI) NM_001131053 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.