Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	F2	HGNC:3535 (HGNC) 2147 (Entrez Gene) 176930 (OMIM) F2 (Alliance of Genome Resources)	Chr11 p11.2	Chr11:46719196-46739506 (+) GRCh38	appendicitis autoimmune hepatitis carotid stenosis celiac disease cerebral infarction coronary artery disease dengue disease eye disease factor VIII deficiency glomerulonephritis hemophilia B herpes zoster myocardial infarction osteonecrosis pre-eclampsia prothrombin deficiency pulmonary embolism retinal vein occlusion sensorineural hearing loss systemic lupus erythematosus thrombophilia due to thrombin defect thrombosis	P00734 (UniProt | EBI) NM_000506 (RefSeq)
mouse	F2	MGI:88380 (MGI) 14061 (Entrez Gene) Gene Tree F2 (Alliance of Genome Resources)	Chr2 50.63 cM	Chr2:91455665-91466759 (-) GRCm39		ENSMUSG00000027249 (Ensembl Gene Model) ENSMUSP00000028681 (Ensembl) ENSMUST00000028681 (Ensembl)
rat	F2	RGD:61996 (Rat Genome Database) 29251 (Entrez Gene) F2 (Alliance of Genome Resources)	Chr3 q24			P18292 (UniProt | EBI) NM_022924 (RefSeq)
zebrafish	f2	ZDB-GENE-030131-4606 (Zebrafish Model Organism Database) 325881 (Entrez Gene) f2 (Alliance of Genome Resources)	Chr7			NP_998555 (RefSeq) NM_213390 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.