Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	CLN8	HGNC:2079 (HGNC) 2055 (Entrez Gene) 607837 (OMIM) CLN8 (Alliance of Genome Resources)	Chr8 p23.3	Chr8:1753059-1801711 (+) GRCh38	neuronal ceroid lipofuscinosis 8 neuronal ceroid lipofuscinosis 8 northern epilepsy variant	Q9UBY8 (UniProt | EBI) NM_018941 (RefSeq)
mouse	Cln8	MGI:1349447 (MGI) 26889 (Entrez Gene) Gene Tree Cln8 (Alliance of Genome Resources)	Chr8 7.59 cM	Chr8:14931335-14951720 (+) GRCm39	neuronal ceroid lipofuscinosis 8	26889 (NCBI Gene Model) Q9QUK3 (UniProt | EBI) NM_001425024 (RefSeq)
rat	Cln8	RGD:1359518 (Rat Genome Database) 306619 (Entrez Gene) Cln8 (Alliance of Genome Resources)	Chr16 q12.5			Q6AYM9 (UniProt | EBI) NM_001007686 (RefSeq)
zebrafish	cln8	ZDB-GENE-060906-3 (Zebrafish Model Organism Database) 100136870 (Entrez Gene) cln8 (Alliance of Genome Resources)	Chr17			NP_001108060 (RefSeq) NM_001114588 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.