Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	ZMPSTE24	HGNC:12877 (HGNC) 10269 (Entrez Gene) 606480 (OMIM) ZMPSTE24 (Alliance of Genome Resources)	Chr1 p34.2	Chr1:40258041-40294180 (+) GRCh38	mandibuloacral dysplasia type B lipodystrophy restrictive dermopathy restrictive dermopathy 1	O75844 (UniProt | EBI) NM_005857 (RefSeq)
mouse	Zmpste24	MGI:1890508 (MGI) 230709 (Entrez Gene) Gene Tree Zmpste24 (Alliance of Genome Resources)	Chr4 56.8 cM	Chr4:120916434-120955438 (-) GRCm39	Emery-Dreifuss muscular dystrophy familial partial lipodystrophy progeria	ENSMUSG00000043207 (Ensembl Gene Model) ENSMUSP00000053900 (Ensembl) ENSMUST00000058754 (Ensembl)
rat	Zmpste24	RGD:1305570 (Rat Genome Database) 313564 (Entrez Gene) Zmpste24 (Alliance of Genome Resources)	Chr5 q36			NP_001101444 (RefSeq) NM_001107974 (RefSeq)
zebrafish	zmpste24	ZDB-GENE-030131-6312 (Zebrafish Model Organism Database) 334380 (Entrez Gene) zmpste24 (Alliance of Genome Resources)	Chr17			NP_956186 (RefSeq) NM_199892 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.