Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	TUBB4B	HGNC:20771 (HGNC) 10383 (Entrez Gene) 602660 (OMIM) TUBB4B (Alliance of Genome Resources)	Chr9 q34.3	Chr9:137241287-137243707 (+) GRCh38	Leber congenital amaurosis with early-onset deafness	P68371 (UniProt | EBI) NM_006088 (RefSeq)
mouse	Tubb4b	MGI:1915472 (MGI) 227613 (Entrez Gene) Gene Tree Tubb4b (Alliance of Genome Resources)	Chr2 17.08 cM	Chr2:25112172-25114714 (-) GRCm39		ENSMUSG00000036752 (Ensembl Gene Model) ENSMUSP00000042342 (Ensembl) ENSMUST00000043584 (Ensembl)
rat	Tubb4b	RGD:735101 (Rat Genome Database) 296554 (Entrez Gene) Tubb4b (Alliance of Genome Resources)	Chr3 p13			Q6P9T8 (UniProt | EBI) NM_199094 (RefSeq)
zebrafish	tubb2b	ZDB-GENE-030131-722 (Zebrafish Model Organism Database) 641421 (Entrez Gene) tubb2b (Alliance of Genome Resources)	Chr8			NP_001032487 (RefSeq) NM_001037410 (RefSeq)
	tubb4b	ZDB-GENE-030131-8625 (Zebrafish Model Organism Database) 336681 (Entrez Gene) tubb4b (Alliance of Genome Resources)	Chr14			NP_942104 (RefSeq) NM_198809 (RefSeq)
	zgc:55461	ZDB-GENE-040426-2879 (Zebrafish Model Organism Database) 406811 (Entrez Gene) zgc:55461 (Alliance of Genome Resources)	Chr5			NP_998655 (RefSeq) NM_213490 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.