Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	SOCS3	HGNC:19391 (HGNC) 9021 (Entrez Gene) 604176 (OMIM) SOCS3 (Alliance of Genome Resources)	Chr17 q25.3	Chr17:78356778-78360925 (-) GRCh38	obesity	O14543 (UniProt | EBI) NM_001378933 (RefSeq)
mouse	Socs3	MGI:1201791 (MGI) 12702 (Entrez Gene) Gene Tree Socs3 (Alliance of Genome Resources)	Chr11 82.96 cM	Chr11:117856905-117860192 (-) GRCm39		12702 (NCBI Gene Model) O35718 (UniProt | EBI) NM_007707 (RefSeq)
rat	Socs3	RGD:621087 (Rat Genome Database) 89829 (Entrez Gene) Socs3 (Alliance of Genome Resources)	Chr10 q32.2			O88583 (UniProt | EBI) NM_053565 (RefSeq)
zebrafish	socs3a	ZDB-GENE-030131-7349 (Zebrafish Model Organism Database) 335409 (Entrez Gene) socs3a (Alliance of Genome Resources)	Chr3			NP_956244 (RefSeq) NM_199950 (RefSeq)
	socs3b	ZDB-GENE-040426-2528 (Zebrafish Model Organism Database) 406596 (Entrez Gene) socs3b (Alliance of Genome Resources)	Chr12			NP_998469 (RefSeq) NM_213304 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.