Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	OTOF	HGNC:8515 (HGNC) 9381 (Entrez Gene) 603681 (OMIM) OTOF (Alliance of Genome Resources)	Chr2 p23.3	Chr2:26457203-26558756 (-) GRCh38	autosomal recessive nonsyndromic deafness 9	Q9HC10 (UniProt | EBI) NM_194323 (RefSeq)
mouse	Otof	MGI:1891247 (MGI) 83762 (Entrez Gene) Gene Tree Otof (Alliance of Genome Resources)	Chr5 16.48 cM	Chr5:30524406-30619276 (-) GRCm39	autosomal recessive nonsyndromic deafness 9	ENSMUSG00000062372 (Ensembl Gene Model) ENSMUSP00000073803 (Ensembl) ENSMUST00000074171 (Ensembl)
rat	Otof	RGD:620646 (Rat Genome Database) 84573 (Entrez Gene) Otof (Alliance of Genome Resources)	Chr6 q14			Q9ERC5 (UniProt | EBI) NM_001276720 (RefSeq)
zebrafish	otofa	ZDB-GENE-030131-7778 (Zebrafish Model Organism Database) 557476 (Entrez Gene) otofa (Alliance of Genome Resources)	Chr20			Q5SPC5 (UniProt | EBI) NM_001030112 (RefSeq)
	otofb	ZDB-GENE-110406-5 (Zebrafish Model Organism Database) 100331283 (Entrez Gene) otofb (Alliance of Genome Resources)	Chr17			XP_017207363 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.