Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	GPRC5B	HGNC:13308 (HGNC) 51704 (Entrez Gene) 605948 (OMIM) GPRC5B (Alliance of Genome Resources)	Chr16 p12.3	Chr16:19856691-19886167 (-) GRCh38	megalencephalic leukoencephalopathy with subcortical cysts	Q9NZH0 (UniProt | EBI) NM_016235 (RefSeq)
mouse	Gprc5b	MGI:1927596 (MGI) 64297 (Entrez Gene) Gene Tree Gprc5b (Alliance of Genome Resources)	Chr7 63.72 cM	Chr7:118571270-118594434 (-) GRCm39		ENSMUSG00000008734 (Ensembl Gene Model) ENSMUSP00000146777 (Ensembl) ENSMUST00000208394 (Ensembl)
rat	Gprc5b	RGD:1309510 (Rat Genome Database) 293546 (Entrez Gene) Gprc5b (Alliance of Genome Resources)	Chr1 q35			NP_001385691 (RefSeq) NM_001106304 (RefSeq)
zebrafish	gprc5ba	ZDB-GENE-030131-8162 (Zebrafish Model Organism Database) 570207 (Entrez Gene) gprc5ba (Alliance of Genome Resources)	Chr3			NP_001311385 (RefSeq) NM_001324456 (RefSeq)
	gprc5bb	ZDB-GENE-090313-75 (Zebrafish Model Organism Database) 100002676 (Entrez Gene) gprc5bb (Alliance of Genome Resources)	Chr1			NP_001139176 (RefSeq) NM_001145704 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.