Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	MYLK	HGNC:7590 (HGNC) 4638 (Entrez Gene) 600922 (OMIM) MYLK (Alliance of Genome Resources)	Chr3 q21.1	Chr3:123610049-123884332 (-) GRCh38	adult respiratory distress syndrome asthma coronary artery disease megacystis-microcolon-intestinal hypoperistalsis syndrome thoracic aortic aneurysm	Q15746 (UniProt | EBI) NM_053027 (RefSeq)
mouse	Mylk	MGI:894806 (MGI) 107589 (Entrez Gene) Gene Tree Mylk (Alliance of Genome Resources)	Chr16 24.49 cM	Chr16:34565580-34822790 (+) GRCm39		ENSMUSG00000022836 (Ensembl Gene Model) ENSMUSP00000023538 (Ensembl) ENSMUST00000023538 (Ensembl)
rat	Mylk	RGD:1310915 (Rat Genome Database) 288057 (Entrez Gene) Mylk (Alliance of Genome Resources)	Chr11 q22			NP_001099344 (RefSeq) NM_001105874 (RefSeq)
zebrafish	mylka	ZDB-GENE-030131-8207 (Zebrafish Model Organism Database) 569510 (Entrez Gene) mylka (Alliance of Genome Resources)	Chr9			XP_009302721 (RefSeq) NM_001105682 (RefSeq)
	mylkb	ZDB-GENE-041111-150 (Zebrafish Model Organism Database) 492576 (Entrez Gene) mylkb (Alliance of Genome Resources)	Chr6			XP_009300538 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.