Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	SEZ6	HGNC:15955 (HGNC) 124925 (Entrez Gene) 616666 (OMIM) SEZ6 (Alliance of Genome Resources)	Chr17 q11.2			Q53EL9 (UniProt | EBI) NM_001290202 (RefSeq)
mouse	Sez6	MGI:104745 (MGI) 20370 (Entrez Gene) Gene Tree Sez6 (Alliance of Genome Resources)	Chr11 46.74 cM	Chr11:77821626-77869874 (+) GRCm39		ENSMUSG00000000632 (Ensembl Gene Model) ENSMUSP00000091532 (Ensembl) ENSMUST00000093995 (Ensembl)
rat	Sez6	RGD:619780 (Rat Genome Database) 192247 (Entrez Gene) Sez6 (Alliance of Genome Resources)	Chr10 q24-q25			NP_001099224 (RefSeq) NM_001105754 (RefSeq)
zebrafish	sez6a	ZDB-GENE-030131-8208 (Zebrafish Model Organism Database) 562079 (Entrez Gene) sez6a (Alliance of Genome Resources)	Chr10			XP_001919970 (RefSeq)
	sez6b	ZDB-GENE-110628-3 (Zebrafish Model Organism Database) 100536906 (Entrez Gene) sez6b (Alliance of Genome Resources)	Chr15			XP_021328618 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.