Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	COL1A2	HGNC:2198 (HGNC) 1278 (Entrez Gene) 120160 (OMIM) COL1A2 (Alliance of Genome Resources)	Chr7 q21.3	Chr7:94394895-94431227 (+) GRCh38	Ehlers-Danlos syndrome Ehlers-Danlos syndrome arthrochalasia type 2 Ehlers-Danlos syndrome cardiac valvular type heart valve disease intracranial aneurysm osteogenesis imperfecta osteogenesis imperfecta type 2 osteogenesis imperfecta type 3 osteogenesis imperfecta type 4 osteoporosis	P08123 (UniProt | EBI) NM_000089 (RefSeq)
mouse	Col1a2	MGI:88468 (MGI) 12843 (Entrez Gene) Gene Tree Col1a2 (Alliance of Genome Resources)	Chr6 1.81 cM	Chr6:4505618-4541543 (+) GRCm39	osteogenesis imperfecta osteogenesis imperfecta type 3	12843 (NCBI Gene Model) Q01149 (UniProt | EBI) NM_007743 (RefSeq)
rat	Col1a2	RGD:621351 (Rat Genome Database) 84352 (Entrez Gene) Col1a2 (Alliance of Genome Resources)	Chr4 q21			P02466 (UniProt | EBI) NM_053356 (RefSeq)
zebrafish	col1a2	ZDB-GENE-030131-8415 (Zebrafish Model Organism Database) 336471 (Entrez Gene) col1a2 (Alliance of Genome Resources)	Chr19			NP_892013 (RefSeq) NM_182968 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.