Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	FGB	HGNC:3662 (HGNC) 2244 (Entrez Gene) 134830 (OMIM) FGB (Alliance of Genome Resources)	Chr4 q31.3	Chr4:154562980-154572807 (+) GRCh38	cardiovascular system disease carotid artery disease congenital afibrinogenemia coronary artery disease end stage renal disease myocardial infarction thrombosis	P02675 (UniProt | EBI) NM_001382760 (RefSeq)
mouse	Fgb	MGI:99501 (MGI) 110135 (Entrez Gene) Gene Tree Fgb (Alliance of Genome Resources)	Chr3 36.98 cM	Chr3:82949553-82957170 (-) GRCm39		110135 (NCBI Gene Model) Q8K0E8 (UniProt | EBI) NM_181849 (RefSeq)
rat	Fgb	RGD:2604 (Rat Genome Database) 24366 (Entrez Gene) Fgb (Alliance of Genome Resources)	Chr2 q34			P14480 (UniProt | EBI) NM_020071 (RefSeq)
zebrafish	fgb	ZDB-GENE-030131-9261 (Zebrafish Model Organism Database) 337315 (Entrez Gene) fgb (Alliance of Genome Resources)	Chr1			NP_997939 (RefSeq) NM_212774 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.