Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	SPAG1	HGNC:11212 (HGNC) 6674 (Entrez Gene) 603395 (OMIM) SPAG1 (Alliance of Genome Resources)	Chr8 q22.2	Chr8:100157906-100259278 (+) GRCh38	primary ciliary dyskinesia 28	Q07617 (UniProt | EBI) NM_001374321 (RefSeq)
mouse	Spag1	MGI:1349387 (MGI) 26942 (Entrez Gene) Gene Tree Spag1 (Alliance of Genome Resources)	Chr15 14.46 cM	Chr15:36178245-36235767 (+) GRCm39		ENSMUSG00000037617 (Ensembl Gene Model) ENSMUSP00000047335 (Ensembl) ENSMUST00000047348 (Ensembl)
rat	Spag1	RGD:1310702 (Rat Genome Database) 315033 (Entrez Gene) Spag1 (Alliance of Genome Resources)	Chr7 q22			Q5U2X2 (UniProt | EBI) NM_001012116 (RefSeq)
zebrafish	spag1a	ZDB-GENE-030131-9443 (Zebrafish Model Organism Database) 564953 (Entrez Gene) spag1a (Alliance of Genome Resources)	Chr19			F1RBN2 (UniProt | EBI) NM_001089406 (RefSeq)
	spag1b	ZDB-GENE-061013-512 (Zebrafish Model Organism Database) 768178 (Entrez Gene) spag1b (Alliance of Genome Resources)	Chr16			NP_001070789 (RefSeq) NM_001077321 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.