Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	SIK1	HGNC:11142 (HGNC) 150094 (Entrez Gene) 605705 (OMIM) SIK1 (Alliance of Genome Resources)	Chr21 q22.3	Chr21:43414483-43427131 (-) GRCh38	developmental and epileptic encephalopathy 30	P57059 (UniProt | EBI) NM_173354 (RefSeq)
mouse	Sik1	MGI:104754 (MGI) 17691 (Entrez Gene) Gene Tree Sik1 (Alliance of Genome Resources)	Chr17 17.25 cM	Chr17:32063224-32074778 (-) GRCm39		ENSMUSG00000024042 (Ensembl Gene Model) ENSMUSP00000024839 (Ensembl) ENSMUST00000024839 (Ensembl)
rat	Sik1	RGD:69407 (Rat Genome Database) 59329 (Entrez Gene) Sik1 (Alliance of Genome Resources)	Chr20 p12			Q9R1U5 (UniProt | EBI) NM_021693 (RefSeq)
zebrafish	sik1	ZDB-GENE-030131-9446 (Zebrafish Model Organism Database) 553465 (Entrez Gene) sik1 (Alliance of Genome Resources)	Chr9			NP_001119855 (RefSeq) NM_001126383 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.