Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	ADK	HGNC:257 (HGNC) 132 (Entrez Gene) 102750 (OMIM) ADK (Alliance of Genome Resources)	Chr10 q22	Chr10:74151202-74709963 (+) GRCh38	hypermethioninemia due to adenosine kinase deficiency	P55263 (UniProt | EBI) NM_001202450 (RefSeq)
mouse	Adk	MGI:87930 (MGI) 11534 (Entrez Gene) Gene Tree Adk (Alliance of Genome Resources)	Chr14 11.58 cM	Chr14:21102642-21498637 (+) GRCm39	steatotic liver disease	ENSMUSG00000039197 (Ensembl Gene Model) ENSMUSP00000047665 (Ensembl) ENSMUST00000045376 (Ensembl)
rat	Adk	RGD:2046 (Rat Genome Database) 25368 (Entrez Gene) Adk (Alliance of Genome Resources)	Chr15 p16			Q64640 (UniProt | EBI) NM_012895 (RefSeq)
zebrafish	adka	ZDB-GENE-030425-3 (Zebrafish Model Organism Database) 368220 (Entrez Gene) adka (Alliance of Genome Resources)	Chr13			NP_001259013 (RefSeq) NM_001272084 (RefSeq)
	adkb	ZDB-GENE-030131-948 (Zebrafish Model Organism Database) 322229 (Entrez Gene) adkb (Alliance of Genome Resources)	Chr12			NP_942097 (RefSeq) NM_198802 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.