Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	CES2	HGNC:1864 (HGNC) 8824 (Entrez Gene) 605278 (OMIM) CES2 (Alliance of Genome Resources)	Chr16 q22.1	Chr16:66934444-66945096 (+) GRCh38		O00748 (UniProt | EBI) NM_001365408 (RefSeq)
mouse	Ces2e	MGI:2443170 (MGI) 234673 (Entrez Gene) Gene Tree Ces2e (Alliance of Genome Resources)	Chr8 53.04 cM	Chr8:105652892-105661304 (+) GRCm39		234673 (NCBI Gene Model) Q8BK48 (UniProt | EBI) NM_172759 (RefSeq)
rat	Ces2e	RGD:621563 (Rat Genome Database) 192257 (Entrez Gene) Ces2e (Alliance of Genome Resources)	Chr19 p14			G3V7J5 (UniProt | EBI) NM_001100477 (RefSeq)
	Ces2el1	RGD:1587637 (Rat Genome Database) 688542 (Entrez Gene) Ces2el1 (Alliance of Genome Resources)	Chr19			NP_001418901 (RefSeq) NM_001431972 (RefSeq)
zebrafish	ces3	ZDB-GENE-030131-9563 (Zebrafish Model Organism Database) 560651 (Entrez Gene) ces3 (Alliance of Genome Resources)	Chr18			NP_001038401 (RefSeq) NM_001044936 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.