Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	POLR2E	HGNC:9192 (HGNC) 5434 (Entrez Gene) 180664 (OMIM) POLR2E (Alliance of Genome Resources)	Chr19 p13.3	Chr19:1086574-1095380 (-) GRCh38		P19388 (UniProt | EBI) NM_001316324 (RefSeq)
mouse	Polr2e	MGI:1913670 (MGI) 66420 (Entrez Gene) Gene Tree Polr2e (Alliance of Genome Resources)	Chr10 39.72 cM	Chr10:79871787-79875493 (-) GRCm39		66420 (NCBI Gene Model) Q80UW8 (UniProt | EBI) NM_025554 (RefSeq)
rat	Polr2e	RGD:1589817 (Rat Genome Database) 690966 (Entrez Gene) Polr2e (Alliance of Genome Resources)	Chr7 q11			B0BNE2 (UniProt | EBI) NM_001109614 (RefSeq)
zebrafish	polr2ea	ZDB-GENE-100630-1 (Zebrafish Model Organism Database) 100330570 (Entrez Gene) polr2ea (Alliance of Genome Resources)	Chr2			XP_068071031 (RefSeq)
	polr2eb	ZDB-GENE-040801-83 (Zebrafish Model Organism Database) 445170 (Entrez Gene) polr2eb (Alliance of Genome Resources)	Chr22			NP_001003564 (RefSeq) NM_001003564 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.