Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	FREM2	HGNC:25396 (HGNC) 341640 (Entrez Gene) 608945 (OMIM) FREM2 (Alliance of Genome Resources)	Chr13 q13.3	Chr13:38687077-38887131 (+) GRCh38	Fraser syndrome 2 isolated cryptophthalmia	Q5SZK8 (UniProt | EBI) NM_207361 (RefSeq)
mouse	Frem2	MGI:2444465 (MGI) 242022 (Entrez Gene) Gene Tree Frem2 (Alliance of Genome Resources)	Chr3 25.24 cM	Chr3:53421359-53564776 (-) GRCm39	Fraser syndrome isolated cryptophthalmia	ENSMUSG00000037016 (Ensembl Gene Model) ENSMUSP00000088670 (Ensembl) ENSMUST00000091137 (Ensembl)
rat	Frem2	RGD:1566012 (Rat Genome Database) 310418 (Entrez Gene) Frem2 (Alliance of Genome Resources)	Chr2 q26			NP_001232907 (RefSeq) NM_001245978 (RefSeq)
zebrafish	frem2a	ZDB-GENE-081119-3 (Zebrafish Model Organism Database) 555681 (Entrez Gene) frem2a (Alliance of Genome Resources)	Chr10			NP_001131129 (RefSeq) NM_001137657 (RefSeq)
	frem2b	ZDB-GENE-081119-4 (Zebrafish Model Organism Database) 566673 (Entrez Gene) frem2b (Alliance of Genome Resources)	Chr15			NP_001131133 (RefSeq) NM_001137661 (RefSeq)
	frem3	ZDB-GENE-030131-9788 (Zebrafish Model Organism Database) 564383 (Entrez Gene) frem3 (Alliance of Genome Resources)	Chr1			NP_001131131 (RefSeq) NM_001137659 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.