Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	HSPB1	HGNC:5246 (HGNC) 3315 (Entrez Gene) 602195 (OMIM) HSPB1 (Alliance of Genome Resources)	Chr7 q11.23	Chr7:76302673-76304295 (+) GRCh38	autosomal dominant distal hereditary motor neuronopathy 3 Charcot-Marie-Tooth disease axonal type 2F pancreatic cancer sarcoma	P04792 (UniProt | EBI) NM_001540 (RefSeq)
mouse	Hspb1	MGI:96240 (MGI) 15507 (Entrez Gene) Gene Tree Hspb1 (Alliance of Genome Resources)	Chr5 75.51 cM	Chr5:135916773-135918417 (+) GRCm39		15507 (NCBI Gene Model) P14602 (UniProt | EBI) NM_013560 (RefSeq)
rat	Hspb1	RGD:61306 (Rat Genome Database) 24471 (Entrez Gene) Hspb1 (Alliance of Genome Resources)	Chr12 q12			P42930 (UniProt | EBI) NM_031970 (RefSeq)
zebrafish	hspb1	ZDB-GENE-030326-4 (Zebrafish Model Organism Database) 368243 (Entrez Gene) hspb1 (Alliance of Genome Resources)	Chr5			NP_001008615 (RefSeq) NM_001008615 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.