Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	DIO1	HGNC:2883 (HGNC) 1733 (Entrez Gene) 147892 (OMIM) DIO1 (Alliance of Genome Resources)	Chr1 p32.3	Chr1:53891239-53911086 (+) GRCh38	thyroid gland disease	P49895 (UniProt | EBI) NM_000792 (RefSeq)
mouse	Dio1	MGI:94896 (MGI) 13370 (Entrez Gene) Gene Tree Dio1 (Alliance of Genome Resources)	Chr4 50.18 cM	Chr4:107148662-107164365 (-) GRCm39		13370 (NCBI Gene Model) Q61153 (UniProt | EBI) NM_007860 (RefSeq)
rat	Dio1	RGD:2504 (Rat Genome Database) 25430 (Entrez Gene) Dio1 (Alliance of Genome Resources)	Chr5 q34			P24389 (UniProt | EBI) NM_021653 (RefSeq)
zebrafish	dio1	ZDB-GENE-030328-41 (Zebrafish Model Organism Database) 799937 (Entrez Gene) dio1 (Alliance of Genome Resources)	Chr8			NP_001007284 (RefSeq) NM_001324404 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.