Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	GPX4	HGNC:4556 (HGNC) 2879 (Entrez Gene) 138322 (OMIM) GPX4 (Alliance of Genome Resources)	Chr19 p13.3	Chr19:1103982-1106791 (+) GRCh38	colorectal adenocarcinoma colorectal cancer spondylometaphyseal dysplasia Sedaghatian type	P36969 (UniProt | EBI) NM_001039848 (RefSeq)
mouse	Gpx4	MGI:104767 (MGI) 625249 (Entrez Gene) Gene Tree Gpx4 (Alliance of Genome Resources)	Chr10 39.72 cM	Chr10:79883000-79892273 (+) GRCm39		625249 (NCBI Gene Model) O70325 (UniProt | EBI) NM_001037741 (RefSeq)
rat	Gpx4	RGD:69226 (Rat Genome Database) 29328 (Entrez Gene) Gpx4 (Alliance of Genome Resources)	Chr7 q11			P36970 (UniProt | EBI) NM_017165 (RefSeq)
zebrafish	gpx4a	ZDB-GENE-030410-2 (Zebrafish Model Organism Database) 352928 (Entrez Gene) gpx4a (Alliance of Genome Resources)	Chr22			NP_001007283 (RefSeq) NM_001346537 (RefSeq)
	gpx4b	ZDB-GENE-030410-3 (Zebrafish Model Organism Database) 352929 (Entrez Gene) gpx4b (Alliance of Genome Resources)	Chr2			NP_001025241 (RefSeq) NM_001030070 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.