Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	STAT4	HGNC:11365 (HGNC) 6775 (Entrez Gene) 600558 (OMIM) STAT4 (Alliance of Genome Resources)	Chr2 q32.2-q32.3	Chr2:191029576-191178435 (-) GRCh38	autoimmune hepatitis Behcet's disease dermatomyositis diffuse scleroderma disabling pansclerotic morphea genital herpes hepatocellular carcinoma IgA glomerulonephritis limited scleroderma polymyositis primary biliary cholangitis psoriasis psoriatic arthritis rectum adenocarcinoma Sjogren's syndrome systemic lupus erythematosus systemic scleroderma Vogt-Koyanagi-Harada disease	Q14765 (UniProt | EBI) NM_001243835 (RefSeq)
mouse	Stat4	MGI:103062 (MGI) 20849 (Entrez Gene) Gene Tree Stat4 (Alliance of Genome Resources)	Chr1 26.67 cM	Chr1:52026307-52146348 (+) GRCm39	type 1 diabetes mellitus	ENSMUSG00000062939 (Ensembl Gene Model) ENSMUSP00000027277 (Ensembl) ENSMUST00000027277 (Ensembl)
zebrafish	stat4	ZDB-GENE-030616-264 (Zebrafish Model Organism Database) 368519 (Entrez Gene) stat4 (Alliance of Genome Resources)	Chr9			NP_001004510 (RefSeq) NM_001004510 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.