Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	ADAM8	HGNC:215 (HGNC) 101 (Entrez Gene) 602267 (OMIM) ADAM8 (Alliance of Genome Resources)	Chr10 q26.3	Chr10:133262420-133276868 (-) GRCh38		P78325 (UniProt | EBI) NM_001164489 (RefSeq)
mouse	Adam8	MGI:107825 (MGI) 11501 (Entrez Gene) Gene Tree Adam8 (Alliance of Genome Resources)	Chr7 84.96 cM	Chr7:139558845-139572475 (-) GRCm39		ENSMUSG00000025473 (Ensembl Gene Model) ENSMUSP00000101684 (Ensembl) ENSMUST00000106069 (Ensembl)
rat	Adam8	RGD:1566394 (Rat Genome Database) 499285 (Entrez Gene) Adam8 (Alliance of Genome Resources)	Chr1 q41			NP_001414053 (RefSeq) NM_001427124 (RefSeq)
zebrafish	adam8a	ZDB-GENE-030616-622 (Zebrafish Model Organism Database) 368917 (Entrez Gene) adam8a (Alliance of Genome Resources)	Chr13			NP_956931 (RefSeq) NM_200637 (RefSeq)
	adam8b	ZDB-GENE-070808-1 (Zebrafish Model Organism Database) 100005593 (Entrez Gene) adam8b (Alliance of Genome Resources)	Chr12			XP_009304791 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.