Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	PENK	HGNC:8831 (HGNC) 5179 (Entrez Gene) 131330 (OMIM) PENK (Alliance of Genome Resources)	Chr8 q12.1	Chr8:56436674-56446671 (-) GRCh38	overactive bladder syndrome	P01210 (UniProt | EBI) NM_001135690 (RefSeq)
mouse	Penk	MGI:104629 (MGI) 18619 (Entrez Gene) Gene Tree Penk (Alliance of Genome Resources)	Chr4 2.31 cM	Chr4:4133536-4138815 (-) GRCm39		18619 (NCBI Gene Model) P22005 (UniProt | EBI) NM_001348209 (RefSeq)
rat	Penk	RGD:68946 (Rat Genome Database) 29237 (Entrez Gene) Penk (Alliance of Genome Resources)	Chr5 q12			P04094 (UniProt | EBI) NM_001429580 (RefSeq)
zebrafish	penka	ZDB-GENE-030729-31 (Zebrafish Model Organism Database) 368228 (Entrez Gene) penka (Alliance of Genome Resources)	Chr2			NP_956377 (RefSeq) NM_200083 (RefSeq)
	penkb	ZDB-GENE-030729-3 (Zebrafish Model Organism Database) 360136 (Entrez Gene) penkb (Alliance of Genome Resources)	Chr7			NP_001410526 (RefSeq) NM_182883 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.