Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	GAD2	HGNC:4093 (HGNC) 2572 (Entrez Gene) 138275 (OMIM) GAD2 (Alliance of Genome Resources)	Chr10 p12.1	Chr10:26216372-26304558 (+) GRCh38	alcohol dependence amphetamine abuse drug psychosis gestational diabetes heroin dependence schizophrenia type 1 diabetes mellitus	Q05329 (UniProt | EBI) NM_001134366 (RefSeq)
mouse	Gad2	MGI:95634 (MGI) 14417 (Entrez Gene) Gene Tree Gad2 (Alliance of Genome Resources)	Chr2 15.15 cM	Chr2:22512262-22583889 (+) GRCm39	epilepsy type 1 diabetes mellitus	14417 (NCBI Gene Model) P48320 (UniProt | EBI) NM_008078 (RefSeq)
rat	Gad2	RGD:2653 (Rat Genome Database) 24380 (Entrez Gene) Gad2 (Alliance of Genome Resources)	Chr17 q12.3			Q05683 (UniProt | EBI) NM_012563 (RefSeq)
zebrafish	gad2	ZDB-GENE-030909-9 (Zebrafish Model Organism Database) 550403 (Entrez Gene) gad2 (Alliance of Genome Resources)	Chr24			NP_001017708 (RefSeq) NM_001017708 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.