Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	ERBB3	HGNC:3431 (HGNC) 2065 (Entrez Gene) 190151 (OMIM) ERBB3 (Alliance of Genome Resources)	Chr12 q13.2	Chr12:56076799-56103505 (+) GRCh38	lethal congenital contracture syndrome 2 lung adenocarcinoma lung non-small cell carcinoma neuronal intestinal dysplasia type A	P21860 (UniProt | EBI) NM_001982 (RefSeq)
mouse	Erbb3	MGI:95411 (MGI) 13867 (Entrez Gene) Gene Tree Erbb3 (Alliance of Genome Resources)	Chr10 77.1 cM	Chr10:128403392-128425504 (-) GRCm39		13867 (NCBI Gene Model) Q61526 (UniProt | EBI) NM_010153 (RefSeq)
rat	Erbb3	RGD:69323 (Rat Genome Database) 29496 (Entrez Gene) Erbb3 (Alliance of Genome Resources)	Chr7 q11			Q62799 (UniProt | EBI) NM_017218 (RefSeq)
zebrafish	erbb3a	ZDB-GENE-030916-3 (Zebrafish Model Organism Database) 386635 (Entrez Gene) erbb3a (Alliance of Genome Resources)	Chr6			NP_001005320 (RefSeq) NM_001005320 (RefSeq)
	erbb3b	ZDB-GENE-050107-1 (Zebrafish Model Organism Database) 544664 (Entrez Gene) erbb3b (Alliance of Genome Resources)	Chr23			NP_001014826 (RefSeq) NM_001014826 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.