Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	GSTT1	HGNC:4641 (HGNC) 2952 (Entrez Gene) 600436 (OMIM) GSTT1 (Alliance of Genome Resources)	Chr22 q11.23		acute chest syndrome acute lymphoblastic leukemia acute myeloid leukemia acute promyelocytic leukemia aggressive periodontitis alcohol dependence Alzheimer's disease aplastic anemia asthma atopic dermatitis beta thalassemia breast cancer bronchopulmonary dysplasia cancer cardiovascular system disease cataract cervical cancer cervix carcinoma chronic obstructive pulmonary disease colorectal adenocarcinoma colorectal cancer colorectal carcinoma congenital heart disease coronary artery disease COVID-19 Crohn's disease cystic fibrosis diabetes mellitus diabetic retinopathy diffuse large B-cell lymphoma drug allergy end stage renal disease esophageal cancer esophagus adenocarcinoma esophagus squamous cell carcinoma exfoliation syndrome Fanconi anemia head and neck cancer hepatocellular carcinoma Hirschsprung's disease Hodgkin's lymphoma hypertension hypospadias infectious mononucleosis inflammatory bowel disease juvenile rheumatoid arthritis Kuhnt-Junius degeneration leukopenia liver cirrhosis liver disease lung cancer lung disease lymphoid leukemia Lynch syndrome medulloblastoma motor neuron disease mucositis multiple myeloma multiple sclerosis myelodysplastic syndrome myeloid leukemia neutropenia optic neuritis oral cavity cancer oral mucosa leukoplakia oral submucous fibrosis orofacial cleft osteonecrosis ovary epithelial cancer pancreatic adenocarcinoma Parkinson's disease peripheral nervous system disease pre-malignant neoplasm primary open angle glaucoma prostate cancer pulmonary tuberculosis renal cell carcinoma rheumatoid arthritis senile cataract sickle cell anemia skin melanoma stomach cancer type 2 diabetes mellitus ulcerative colitis urinary bladder cancer venous insufficiency	P30711 (UniProt | EBI) NM_001293814 (RefSeq)
mouse	Gstt1	MGI:107379 (MGI) 14871 (Entrez Gene) Gene Tree Gstt1 (Alliance of Genome Resources)	Chr10 38.58 cM	Chr10:75619647-75634418 (-) GRCm39		14871 (NCBI Gene Model) Q64471 (UniProt | EBI) NM_008185 (RefSeq)
rat	Gstt1	RGD:2765 (Rat Genome Database) 25260 (Entrez Gene) Gstt1 (Alliance of Genome Resources)	Chr20 p12			Q01579 (UniProt | EBI) NM_053293 (RefSeq)
zebrafish	gstt1a	ZDB-GENE-031001-13 (Zebrafish Model Organism Database) 563972 (Entrez Gene) gstt1a (Alliance of Genome Resources)	Chr8			NP_001314691 (RefSeq) NM_001327762 (RefSeq)
	gstt1b	ZDB-GENE-040426-1491 (Zebrafish Model Organism Database) 393556 (Entrez Gene) gstt1b (Alliance of Genome Resources)	Chr21			NP_956878 (RefSeq) NM_200584 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.