Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	TTC21B	HGNC:25660 (HGNC) 79809 (Entrez Gene) 612014 (OMIM) TTC21B (Alliance of Genome Resources)	Chr2 q24.3	Chr2:165857475-165953851 (-) GRCh38	asphyxiating thoracic dystrophy 4 nephronophthisis 12	Q7Z4L5 (UniProt | EBI) NM_024753 (RefSeq)
mouse	Ttc21b	MGI:1920918 (MGI) 73668 (Entrez Gene) Gene Tree Ttc21b (Alliance of Genome Resources)	Chr2 39.08 cM	Chr2:66014671-66086961 (-) GRCm39	cystic kidney disease	ENSMUSG00000034848 (Ensembl Gene Model) ENSMUSP00000099779 (Ensembl) ENSMUST00000102718 (Ensembl)
rat	Ttc21b	RGD:1565122 (Rat Genome Database) 295654 (Entrez Gene) Ttc21b (Alliance of Genome Resources)	Chr3 q21			NP_001178666 (RefSeq) NM_001191737 (RefSeq)
zebrafish	ttc21b	ZDB-GENE-031010-34 (Zebrafish Model Organism Database) 569823 (Entrez Gene) ttc21b (Alliance of Genome Resources)	Chr9			NP_001121730 (RefSeq) NM_001128258 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.