Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	APH1B	HGNC:24080 (HGNC) 83464 (Entrez Gene) 607630 (OMIM) APH1B (Alliance of Genome Resources)	Chr15 q22.2	Chr15:63276018-63309126 (+) GRCh38	coronary artery disease	Q8WW43 (UniProt | EBI) NM_031301 (RefSeq)
mouse	Aph1c	MGI:1915568 (MGI) 68318 (Entrez Gene) Gene Tree Aph1c (Alliance of Genome Resources)	Chr9 36.15 cM	Chr9:66722276-66741953 (-) GRCm39		68318 (NCBI Gene Model) Q9DCZ9 (UniProt | EBI) NM_001410494 (RefSeq)
rat	Aph1b	RGD:1562468 (Rat Genome Database) 300802 (Entrez Gene) Aph1b (Alliance of Genome Resources)	Chr8 q24			NP_001040555 (RefSeq) NM_001047090 (RefSeq)
zebrafish	aph1b	ZDB-GENE-031118-31 (Zebrafish Model Organism Database) 386808 (Entrez Gene) aph1b (Alliance of Genome Resources)	Chr7			Q8JHE9 (UniProt | EBI) NM_200115 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.