Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	JAM2	HGNC:14686 (HGNC) 58494 (Entrez Gene) 606870 (OMIM) JAM2 (Alliance of Genome Resources)	Chr21 q21.3	Chr21:25639258-25717562 (+) GRCh38	basal ganglia calcification	P57087 (UniProt | EBI) NM_001270408 (RefSeq)
mouse	Jam2	MGI:1933820 (MGI) 67374 (Entrez Gene) Gene Tree Jam2 (Alliance of Genome Resources)	Chr16 46.92 cM	Chr16:84571011-84622816 (+) GRCm39		ENSMUSG00000053062 (Ensembl Gene Model) ENSMUSP00000156235 (Ensembl) ENSMUST00000231910 (Ensembl)
rat	Jam2	RGD:1561692 (Rat Genome Database) 619374 (Entrez Gene) Jam2 (Alliance of Genome Resources)	Chr11 q11			NP_001029176 (RefSeq) NM_001034004 (RefSeq)
zebrafish	jam2a	ZDB-GENE-031204-3 (Zebrafish Model Organism Database) 100005261 (Entrez Gene) jam2a (Alliance of Genome Resources)	Chr1			A0A0R4IGV4 (UniProt | EBI) NM_001098264 (RefSeq)
	jam2b	ZDB-GENE-080229-3 (Zebrafish Model Organism Database) 100005301 (Entrez Gene) jam2b (Alliance of Genome Resources)	Chr9			NP_001121766 (RefSeq) NM_001128294 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.