Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	CHRNA2	HGNC:1956 (HGNC) 1135 (Entrez Gene) 118502 (OMIM) CHRNA2 (Alliance of Genome Resources)	Chr8 p21.2	Chr8:27459756-27479883 (-) GRCh38	autosomal dominant nocturnal frontal lobe epilepsy 4 benign familial infantile seizures 6	Q15822 (UniProt | EBI) NM_001347706 (RefSeq)
mouse	Chrna2	MGI:87886 (MGI) 110902 (Entrez Gene) Gene Tree Chrna2 (Alliance of Genome Resources)	Chr14 34.36 cM	Chr14:66372488-66390397 (+) GRCm39		ENSMUSG00000022041 (Ensembl Gene Model) ENSMUSP00000145896 (Ensembl) ENSMUST00000206455 (Ensembl)
rat	Chrna2	RGD:621533 (Rat Genome Database) 170945 (Entrez Gene) Chrna2 (Alliance of Genome Resources)	Chr15 p12			P12389 (UniProt | EBI) NM_133420 (RefSeq)
zebrafish	chrna2a	ZDB-GENE-040108-2 (Zebrafish Model Organism Database) 678575 (Entrez Gene) chrna2a (Alliance of Genome Resources)	Chr17			NP_001035417 (RefSeq) NM_001040327 (RefSeq)
	chrna2b	ZDB-GENE-041001-99 (Zebrafish Model Organism Database) 568849 (Entrez Gene) chrna2b (Alliance of Genome Resources)	Chr20			XP_021324289 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.