Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	PAFAH1B1	HGNC:8574 (HGNC) 5048 (Entrez Gene) 601545 (OMIM) PAFAH1B1 (Alliance of Genome Resources)	Chr17 p13.3	Chr17:2593183-2685615 (+) GRCh38	lissencephaly lissencephaly 1	P43034 (UniProt | EBI) NM_000430 (RefSeq)
mouse	Pafah1b1	MGI:109520 (MGI) 18472 (Entrez Gene) Gene Tree Pafah1b1 (Alliance of Genome Resources)	Chr11 45.76 cM	Chr11:74564775-74615210 (-) GRCm39	lissencephaly Miller-Dieker lissencephaly syndrome	18472 (NCBI Gene Model) P63005 (UniProt | EBI) NR_037610 (RefSeq)
rat	Pafah1b1	RGD:620331 (Rat Genome Database) 83572 (Entrez Gene) Pafah1b1 (Alliance of Genome Resources)	Chr10 q24			P63004 (UniProt | EBI) NM_031763 (RefSeq)
zebrafish	pafah1b1a	ZDB-GENE-040116-2 (Zebrafish Model Organism Database) 394246 (Entrez Gene) pafah1b1a (Alliance of Genome Resources)	Chr15			Q7T394 (UniProt | EBI) NM_201345 (RefSeq)
	pafah1b1b	ZDB-GENE-040116-3 (Zebrafish Model Organism Database) 394247 (Entrez Gene) pafah1b1b (Alliance of Genome Resources)	Chr21			Q803D2 (UniProt | EBI) NM_201346 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.