Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	MAPK3	HGNC:6877 (HGNC) 5595 (Entrez Gene) 601795 (OMIM) MAPK3 (Alliance of Genome Resources)	Chr16 p11.2	Chr16:30114105-30123506 (-) GRCh38	colon adenocarcinoma colorectal adenocarcinoma endometrial adenocarcinoma pancreatic ductal carcinoma Parkinson's disease pulmonary hypertension	P27361 (UniProt | EBI) NM_002746 (RefSeq)
mouse	Mapk3	MGI:1346859 (MGI) 26417 (Entrez Gene) Gene Tree Mapk3 (Alliance of Genome Resources)	Chr7 69.25 cM	Chr7:126358798-126364988 (+) GRCm39		26417 (NCBI Gene Model) Q63844 (UniProt | EBI) NM_011952 (RefSeq)
rat	Mapk3	RGD:3046 (Rat Genome Database) 50689 (Entrez Gene) Mapk3 (Alliance of Genome Resources)	Chr1 q36			P21708 (UniProt | EBI) NM_017347 (RefSeq)
zebrafish	mapk3	ZDB-GENE-040121-1 (Zebrafish Model Organism Database) 399480 (Entrez Gene) mapk3 (Alliance of Genome Resources)	Chr3			NP_958915 (RefSeq) NM_201507 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.