Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	GNMT	HGNC:4415 (HGNC) 27232 (Entrez Gene) 606628 (OMIM) GNMT (Alliance of Genome Resources)	Chr6 p21.1	Chr6:42960754-42963880 (+) GRCh38	glycine N-methyltransferase deficiency	Q14749 (UniProt | EBI) NM_001318865 (RefSeq)
mouse	Gnmt	MGI:1202304 (MGI) 14711 (Entrez Gene) Gene Tree Gnmt (Alliance of Genome Resources)	Chr17 22.9 cM	Chr17:47036590-47040091 (-) GRCm39	glycine N-methyltransferase deficiency hepatocellular carcinoma	14711 (NCBI Gene Model) Q9QXF8 (UniProt | EBI) NM_001413152 (RefSeq)
rat	Gnmt	RGD:2719 (Rat Genome Database) 25134 (Entrez Gene) Gnmt (Alliance of Genome Resources)	Chr9 q12			P13255 (UniProt | EBI) NM_017084 (RefSeq)
zebrafish	gnmt	ZDB-GENE-040227-1 (Zebrafish Model Organism Database) 403338 (Entrez Gene) gnmt (Alliance of Genome Resources)	Chr17			NP_997981 (RefSeq) NM_212816 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.