Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	GJA5	HGNC:4279 (HGNC) 2702 (Entrez Gene) 121013 (OMIM) GJA5 (Alliance of Genome Resources)	Chr1 q21.2	Chr1:147756199-147773362 (-) GRCh38	atrial fibrillation atrial standstill 1 familial atrial fibrillation tetralogy of Fallot	P36382 (UniProt | EBI) NM_181703 (RefSeq)
mouse	Gja5	MGI:95716 (MGI) 14613 (Entrez Gene) Gene Tree Gja5 (Alliance of Genome Resources)	Chr3 42.04 cM	Chr3:96939718-96960950 (+) GRCm39	tetralogy of Fallot	14613 (NCBI Gene Model) Q01231 (UniProt | EBI) NM_001271628 (RefSeq)
rat	Gja5	RGD:2692 (Rat Genome Database) 50563 (Entrez Gene) Gja5 (Alliance of Genome Resources)	Chr2 q34			P28234 (UniProt | EBI) NM_019280 (RefSeq)
zebrafish	gja5a	ZDB-GENE-040407-3 (Zebrafish Model Organism Database) 404729 (Entrez Gene) gja5a (Alliance of Genome Resources)	Chr9			NP_001007214 (RefSeq) NM_001007213 (RefSeq)
	gja5b	ZDB-GENE-050616-11 (Zebrafish Model Organism Database) 570445 (Entrez Gene) gja5b (Alliance of Genome Resources)	Chr1			NP_001030160 (RefSeq) NM_001034988 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.