Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	DEF8	HGNC:25969 (HGNC) 54849 (Entrez Gene) DEF8 (Alliance of Genome Resources)	Chr16 q24.3	Chr16:89948697-89968060 (+) GRCh38		Q6ZN54 (UniProt | EBI) NM_001242817 (RefSeq)
mouse	Def8	MGI:1346331 (MGI) 23854 (Entrez Gene) Gene Tree Def8 (Alliance of Genome Resources)	Chr8 72.1 cM	Chr8:124169725-124190009 (+) GRCm39		23854 (NCBI Gene Model) Q99J78 (UniProt | EBI) NM_001414287 (RefSeq)
rat	Def8	RGD:1309008 (Rat Genome Database) 307973 (Entrez Gene) Def8 (Alliance of Genome Resources)	Chr19 q12			Q4V8I4 (UniProt | EBI) NM_001024774 (RefSeq)
zebrafish	def8	ZDB-GENE-041114-96 (Zebrafish Model Organism Database) 492523 (Entrez Gene) def8 (Alliance of Genome Resources)	Chr18			NP_001315135 (RefSeq) NM_001007395 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.