Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	CSTA	HGNC:2481 (HGNC) 1475 (Entrez Gene) 184600 (OMIM) CSTA (Alliance of Genome Resources)	Chr3 q21.1	Chr3:122325248-122341969 (+) GRCh38	peeling skin syndrome 4	P01040 (UniProt | EBI) NM_005213 (RefSeq)
mouse	Csta3	MGI:3644688 (MGI) 408196 (Entrez Gene) Gene Tree Csta3 (Alliance of Genome Resources)	Chr16 25.43 cM	Chr16:36030773-36038158 (+) GRCm39		408196 (NCBI Gene Model) NP_001076011 (RefSeq) NM_001082542 (RefSeq)
rat	Csta3	RGD:1594822 (Rat Genome Database) 689230 (Entrez Gene) Csta3 (Alliance of Genome Resources)	Chr11 q22			XP_001070063 (RefSeq)
zebrafish	cst14a.1	ZDB-GENE-141031-1 (Zebrafish Model Organism Database) 573769 (Entrez Gene) cst14a.1 (Alliance of Genome Resources)	Chr24			NP_001303248 (RefSeq) NM_001316319 (RefSeq)
	cst14a.2	ZDB-GENE-040426-1065 (Zebrafish Model Organism Database) 792225 (Entrez Gene) cst14a.2 (Alliance of Genome Resources)	Chr24			NP_001096599 (RefSeq) NM_001103129 (RefSeq)
	cst14b.1	ZDB-GENE-061013-189 (Zebrafish Model Organism Database) 768128 (Entrez Gene) cst14b.1 (Alliance of Genome Resources)	Chr5			NP_001070742 (RefSeq) NM_001077274 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.