Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	KLHL24	HGNC:25947 (HGNC) 54800 (Entrez Gene) 611295 (OMIM) KLHL24 (Alliance of Genome Resources)	Chr3 q27.1	Chr3:183635610-183684519 (+) GRCh38	epidermolysis bullosa simplex familial hypertrophic cardiomyopathy	Q6TFL4 (UniProt | EBI) NM_017644 (RefSeq)
mouse	Klhl24	MGI:1923035 (MGI) 75785 (Entrez Gene) Gene Tree Klhl24 (Alliance of Genome Resources)	Chr16 12.36 cM	Chr16:19916292-19947971 (+) GRCm39		ENSMUSG00000062901 (Ensembl Gene Model) ENSMUSP00000023509 (Ensembl) ENSMUST00000023509 (Ensembl)
rat	Klhl24	RGD:727971 (Rat Genome Database) 303803 (Entrez Gene) Klhl24 (Alliance of Genome Resources)	Chr11 q23			Q56A24 (UniProt | EBI) NM_001394229 (RefSeq)
zebrafish	klhl24a	ZDB-GENE-061013-572 (Zebrafish Model Organism Database) 768198 (Entrez Gene) klhl24a (Alliance of Genome Resources)	Chr2			Q08BL9 (UniProt | EBI) NM_001077340 (RefSeq)
	klhl24b	ZDB-GENE-040426-1185 (Zebrafish Model Organism Database) 393412 (Entrez Gene) klhl24b (Alliance of Genome Resources)	Chr24			NP_956734 (RefSeq) NM_200440 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.