Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	PRKG1	HGNC:9414 (HGNC) 5592 (Entrez Gene) 176894 (OMIM) PRKG1 (Alliance of Genome Resources)	Chr10 q11.23-q21.1	Chr10:50990888-52298423 (+) GRCh38	thoracic aortic aneurysm	Q13976 (UniProt | EBI) NM_001374782 (RefSeq)
mouse	Prkg1	MGI:108174 (MGI) 19091 (Entrez Gene) Gene Tree Prkg1 (Alliance of Genome Resources)	Chr19 25.17 cM	Chr19:30541889-31742433 (-) GRCm39		ENSMUSG00000052920 (Ensembl Gene Model) ENSMUSP00000073268 (Ensembl) ENSMUST00000073581 (Ensembl)
zebrafish	prkg1a	ZDB-GENE-040426-1308 (Zebrafish Model Organism Database) 394005 (Entrez Gene) prkg1a (Alliance of Genome Resources)	Chr13			NP_957324 (RefSeq) NM_201030 (RefSeq)
	prkg1b	ZDB-GENE-080225-40 (Zebrafish Model Organism Database) 566430 (Entrez Gene) prkg1b (Alliance of Genome Resources)	Chr12			XP_068080801 (RefSeq)
	prkg1l	ZDB-GENE-140422-2 (Zebrafish Model Organism Database) 100535807 (Entrez Gene) prkg1l (Alliance of Genome Resources)	Chr8			XP_017213035 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.