Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	RPS6KB1	HGNC:10436 (HGNC) 6198 (Entrez Gene) 608938 (OMIM) RPS6KB1 (Alliance of Genome Resources)	Chr17 q23.1	Chr17:59893046-59950574 (+) GRCh38		P23443 (UniProt | EBI) NM_001369676 (RefSeq)
mouse	Rps6kb1	MGI:1270849 (MGI) 72508 (Entrez Gene) Gene Tree Rps6kb1 (Alliance of Genome Resources)	Chr11 51.82 cM	Chr11:86389697-86435631 (-) GRCm39		ENSMUSG00000020516 (Ensembl Gene Model) ENSMUSP00000119715 (Ensembl) ENSMUST00000154617 (Ensembl)
rat	Rps6kb1	RGD:620683 (Rat Genome Database) 83840 (Entrez Gene) Rps6kb1 (Alliance of Genome Resources)	Chr10 q26			P67999 (UniProt | EBI) NM_031985 (RefSeq)
zebrafish	rps6kb1a	ZDB-GENE-091113-52 (Zebrafish Model Organism Database) 562242 (Entrez Gene) rps6kb1a (Alliance of Genome Resources)	Chr10			XP_690726 (RefSeq)
	rps6kb1b	ZDB-GENE-040426-2038 (Zebrafish Model Organism Database) 406349 (Entrez Gene) rps6kb1b (Alliance of Genome Resources)	Chr15			NP_998241 (RefSeq) NM_213076 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.