Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	LOX	HGNC:6664 (HGNC) 4015 (Entrez Gene) 153455 (OMIM) LOX (Alliance of Genome Resources)	Chr5 q23.1	Chr5:122063195-122078413 (-) GRCh38	colon adenocarcinoma Ehlers-Danlos syndrome hypertension Menkes disease thoracic aortic aneurysm	P28300 (UniProt | EBI) NM_001317073 (RefSeq)
mouse	Lox	MGI:96817 (MGI) 16948 (Entrez Gene) Gene Tree Lox (Alliance of Genome Resources)	Chr18 28.22 cM	Chr18:52649139-52662939 (-) GRCm39	Menkes disease Williams-Beuren syndrome	ENSMUSG00000024529 (Ensembl Gene Model) ENSMUSP00000025409 (Ensembl) ENSMUST00000025409 (Ensembl)
rat	Lox	RGD:3015 (Rat Genome Database) 24914 (Entrez Gene) Lox (Alliance of Genome Resources)	Chr18 q11			P16636 (UniProt | EBI) NM_001414003 (RefSeq)
zebrafish	loxa	ZDB-GENE-040426-2398 (Zebrafish Model Organism Database) 404621 (Entrez Gene) loxa (Alliance of Genome Resources)	Chr10			NP_996972 (RefSeq) NM_207089 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.