Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	PPT1	HGNC:9325 (HGNC) 5538 (Entrez Gene) 600722 (OMIM) PPT1 (Alliance of Genome Resources)	Chr1 p34.2	Chr1:40071461-40097260 (-) GRCh38	neuronal ceroid lipofuscinosis 1	P50897 (UniProt | EBI) NM_001142604 (RefSeq)
mouse	Ppt1	MGI:1298204 (MGI) 19063 (Entrez Gene) Gene Tree Ppt1 (Alliance of Genome Resources)	Chr4 57.27 cM	Chr4:122730035-122752968 (+) GRCm39	neuronal ceroid lipofuscinosis 1 neuronal ceroid lipofuscinosis 3	ENSMUSG00000028657 (Ensembl Gene Model) ENSMUSP00000030412 (Ensembl) ENSMUST00000030412 (Ensembl)
rat	Ppt1	RGD:61994 (Rat Genome Database) 29411 (Entrez Gene) Ppt1 (Alliance of Genome Resources)	Chr5 q36			P45479 (UniProt | EBI) NM_022502 (RefSeq)
zebrafish	ppt1	ZDB-GENE-040426-2653 (Zebrafish Model Organism Database) 406648 (Entrez Gene) ppt1 (Alliance of Genome Resources)	Chr19			NP_998504 (RefSeq) NM_213339 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.