Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	SMPD4	HGNC:32949 (HGNC) 55627 (Entrez Gene) 610457 (OMIM) SMPD4 (Alliance of Genome Resources)	Chr2 q21.1	Chr2:130151392-130182750 (-) GRCh38		Q9NXE4 (UniProt | EBI) NM_017751 (RefSeq)
mouse	Smpd4	MGI:1924876 (MGI) 77626 (Entrez Gene) Gene Tree Smpd4 (Alliance of Genome Resources)	Chr16 10.92 cM	Chr16:17437218-17462692 (+) GRCm39		ENSMUSG00000005899 (Ensembl Gene Model) ENSMUSP00000006053 (Ensembl) ENSMUST00000006053 (Ensembl)
rat	Smpd4	RGD:1310674 (Rat Genome Database) 303790 (Entrez Gene) Smpd4 (Alliance of Genome Resources)	Chr11 q23			NP_001161278 (RefSeq) NM_001167806 (RefSeq)
zebrafish	smpd4	ZDB-GENE-040426-2672 (Zebrafish Model Organism Database) 793294 (Entrez Gene) smpd4 (Alliance of Genome Resources)	Chr21			Q6PFJ7 (UniProt | EBI) NM_213355 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.