Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	PFKFB3	HGNC:8874 (HGNC) 5209 (Entrez Gene) 605319 (OMIM) PFKFB3 (Alliance of Genome Resources)	Chr10 p15.1	Chr10:6144921-6326637 (+) GRCh38		Q16875 (UniProt | EBI) NM_001323017 (RefSeq)
mouse	Pfkfb3	MGI:2181202 (MGI) 170768 (Entrez Gene) Gene Tree Pfkfb3 (Alliance of Genome Resources)	Chr2 8.73 cM	Chr2:11476241-11558882 (-) GRCm39	extrinsic cardiomyopathy	170768 (NCBI Gene Model) NP_001171224 (RefSeq) NM_001177753 (RefSeq)
rat	Pfkfb3	RGD:619776 (Rat Genome Database) 117276 (Entrez Gene) Pfkfb3 (Alliance of Genome Resources)	Chr17 q12.2			O35552 (UniProt | EBI) NM_057135 (RefSeq)
zebrafish	pfkfb3	ZDB-GENE-040426-2724 (Zebrafish Model Organism Database) 554477 (Entrez Gene) pfkfb3 (Alliance of Genome Resources)	Chr4			NP_998562 (RefSeq) NM_213397 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.