Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	TYMS	HGNC:12441 (HGNC) 7298 (Entrez Gene) 188350 (OMIM) TYMS (Alliance of Genome Resources)	Chr18 p11.32	Chr18:657653-673578 (+) GRCh38	abdominal aortic aneurysm acute lymphoblastic leukemia acute myeloid leukemia cerebral infarction colon carcinoma dyskeratosis congenita hepatocellular carcinoma multiple myeloma rheumatoid arthritis	P04818 (UniProt | EBI) NM_001354867 (RefSeq)
mouse	Tyms	MGI:98878 (MGI) 22171 (Entrez Gene) Gene Tree Tyms (Alliance of Genome Resources)	Chr5 15.81 cM	Chr5:30263200-30278615 (-) GRCm39		ENSMUSG00000025747 (Ensembl Gene Model) ENSMUSP00000026846 (Ensembl) ENSMUST00000026846 (Ensembl)
rat	Tyms	RGD:3921 (Rat Genome Database) 29261 (Entrez Gene) Tyms (Alliance of Genome Resources)	Chr9 q38			P45352 (UniProt | EBI) NM_019179 (RefSeq)
zebrafish	tyms	ZDB-GENE-040426-59 (Zebrafish Model Organism Database) 81540 (Entrez Gene) tyms (Alliance of Genome Resources)	Chr7			NP_571835 (RefSeq) NM_131760 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.