Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	SRP54	HGNC:11301 (HGNC) 6729 (Entrez Gene) 604857 (OMIM) SRP54 (Alliance of Genome Resources)	Chr14 q13.2	Chr14:34981957-35029686 (+) GRCh38	severe congenital neutropenia 8	P61011 (UniProt | EBI) NM_001411017 (RefSeq)
mouse	Srp54b	MGI:3714357 (MGI) 665155 (Entrez Gene) Gene Tree Srp54b (Alliance of Genome Resources)	Chr12 23.87 cM	Chr12:55201889-55235998 (+) GRCm39		665155 (NCBI Gene Model) NP_001093579 (RefSeq) NM_001100109 (RefSeq)
rat	Srp54a	RGD:621390 (Rat Genome Database) 116650 (Entrez Gene) Srp54a (Alliance of Genome Resources)	Chr6 q23			Q6AYB5 (UniProt | EBI) NM_053871 (RefSeq)
zebrafish	srp54	ZDB-GENE-040426-818 (Zebrafish Model Organism Database) 393963 (Entrez Gene) srp54 (Alliance of Genome Resources)	Chr17			Q7ZVN5 (UniProt | EBI) NM_200988 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.