Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	SDHA	HGNC:10680 (HGNC) 6389 (Entrez Gene) 600857 (OMIM) SDHA (Alliance of Genome Resources)	Chr5 p15.33	Chr5:218303-268746 (+) GRCh38	dilated cardiomyopathy 1GG Leigh disease lung non-small cell carcinoma mitochondrial complex II deficiency paraganglioma	P31040 (UniProt | EBI) NM_004168 (RefSeq)
mouse	Sdha	MGI:1914195 (MGI) 66945 (Entrez Gene) Gene Tree Sdha (Alliance of Genome Resources)	Chr13 40.15 cM	Chr13:74470374-74498359 (-) GRCm39		66945 (NCBI Gene Model) Q8K2B3 (UniProt | EBI) NM_023281 (RefSeq)
rat	Sdha	RGD:621557 (Rat Genome Database) 157074 (Entrez Gene) Sdha (Alliance of Genome Resources)	Chr1 p11			Q920L2 (UniProt | EBI) NM_130428 (RefSeq)
zebrafish	sdha	ZDB-GENE-040426-874 (Zebrafish Model Organism Database) 393884 (Entrez Gene) sdha (Alliance of Genome Resources)	Chr19			Q7ZVF3 (UniProt | EBI) NM_200910 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.